Global Small Molecule API Market 2020-2027

Bonafide Trust 28-04-2021 165 Pages Figures : 85 Tables : 85
Region : Global Category : Lifescience Healthcare

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Global small molecule active pharmaceutical ingredient (API) market will reach $266.2 billion by 2027, growing by 7.3% annually over 2020-2027 owing to increasing incidences of diseases, development of companies engaged in the manufacturing of small molecule APIs, the increasing technological developments in manufacturing sector, and surge in healthcare expenditure amid COVID-19 pandemic. Highlighted with 85 tables and 85 figures, this 165-page report “Global Small Molecule API Market 2020-2027 by Source (Synthetic, Semi-synthetic, Natural), Type (Standard, HPAPI), Therapeutic Area, Application (Clinical, Commercial), Manufacturer Type (Pharma, CMO), and Region: Trend Forecast and Growth Opportunity” is based on a comprehensive research of the entire global small molecule API market and all its sub-segments through extensively detailed classifications. Profound analysis and assessment are generated from premium primary and secondary information sources with inputs derived from industry professionals across the value chain. The report is based on studies on 2017-2019 and provides estimate for 2020 and forecast from 2021 till 2027 with 2019 as the base year. (Please note: The report will be updated before delivery so that the latest historical year is the base year and the forecast covers at least 5 years over the base year.) In-depth qualitative analyses include identification and investigation of the following aspects: • Market Structure • Growth Drivers • Restraints and Challenges • Emerging Product Trends & Market Opportunities • Porter’s Fiver Forces The trend and outlook of global market is forecast in optimistic, balanced, and conservative view by taking into account of COVID-19. The balanced (most likely) projection is used to quantify global small molecule API market in every aspect of the classification from perspectives of Source, Type, Therapeutic Area, Application, Manufacturer Type, and Region. Based on Source, the global market is segmented into the following sub-markets with annual revenue ($ bn) for 2017-2027 included in each section. • Synthetic API o Branded Synthetic API o Generic Synthetic API • Semi-synthetic API • Natural Origin Based on Type, the global market is segmented into the following sub-markets with annual revenue ($ bn) for 2017-2027 included in each section. • Standard API • High Potency API (HPAPI) o Branded HPAPI o Generic HPAPI Based on Therapeutic Area, the global market is segmented into the following sub-markets with annual revenue ($ bn) for 2017-2027 included in each section. • Infectious Diseases • Oncology • Ophthalmology • Cardiovascular Disorders • Central Nervous System • Respiratory Disorders • Metabolic Diseases • Other Applications Based on Application, the global market is segmented into the following sub-markets with annual revenue ($ bn) for 2017-2027 included in each section. o Clinical Use o Commercial Use Based on Manufacturer Type, the global market is segmented into the following sub-markets with annual revenue ($ bn) for 2017-2027 included in each section. • Pharmaceutical Companies (also breakdown by region) • CMOs (also breakdown by region) Geographically, the following regions together with the listed national/local markets are fully investigated: • APAC (Japan, China, South Korea, Australia, India, and Rest of APAC; Rest of APAC is further segmented into Malaysia, Singapore, Indonesia, Thailand, New Zealand, Vietnam, Taiwan, and Philippines) • Europe (Germany, UK, France, Spain, Italy, Russia, Rest of Europe; Rest of Europe is further segmented into Netherlands, Switzerland, Poland, Sweden, Belgium, Austria, Ireland, Norway, Denmark, and Finland) • North America (U.S., Canada, and Mexico) • South America (Brazil, Chile, Argentina, Rest of South America) • MEA (UAE, Saudi Arabia, South Africa) For each aforementioned region and country, detailed analysis and data for annual revenue ($ bn) are available for 2017-2027. The breakdown of all regional markets by country and split of key national markets by Type, Therapeutic Area, and Manufacturer Type over the forecast years are also included. The report also covers current competitive scenario and the predicted trend; and profiles key vendors including market leaders and important emerging players. Key Players (this may not be a complete list and extra companies can be added upon request): Aurobindo Pharma Ltd. Cambrex Corporation Catalent, Inc. Dr. Reddy's Laboratories Ltd. GlaxoSmithKline plc Lonza Group Merck & Co., Inc. Mylan N.V. Novartis AG Pfizer Inc. Sun Pharmaceutical Industries Ltd. Teva Pharmaceutical Industries Ltd. Wuxi AppTec Co., Ltd. (Please note: The report will be updated before delivery so that the latest historical year is the base year and the forecast covers at least 5 years over the base year.)

1 Introduction 8

1.1 Industry Definition and Research Scope 8

1.1.1 Industry Definition 8

1.1.2 Research Scope 9

1.2 Research Methodology 12

1.2.1 Overview of Market Research Methodology 12

1.2.2 Market Assumption 13

1.2.3 Secondary Data 13

1.2.4 Primary Data 13

1.2.5 Data Filtration and Model Design 15

1.2.6 Market Size/Share Estimation 16

1.2.7 Research Limitations 17

1.3 Executive Summary 18

2 Market Overview and Dynamics 21

2.1 Market Size and Forecast 21

2.1.1 Impact of COVID-19 on World Economy 22

2.1.2 Impact of COVID-19 on the Market 24

2.2 Major Growth Drivers 26

2.3 Market Restraints and Challenges 29

2.4 Emerging Opportunities and Market Trends 32

2.5 Porter’s Fiver Forces Analysis 36

3 Segmentation of Global Market by Source 40

3.1 Market Overview by Source 40

3.2 Synthetic API 42

3.2.1 Branded Synthetic API 43

3.2.2 Generic Synthetic API 44

3.3 Semi-synthetic API 45

3.4 Natural Origin 46

4 Segmentation of Global Market by Type 47

4.1 Market Overview by Type 47

4.2 Standard API 49

4.3 High Potency API (HPAPI) 50

4.3.1 Branded HPAPI 51

4.3.2 Generic HPAPI 52

5 Segmentation of Global Market by Therapeutic Area 53

5.1 Market Overview by Therapeutic Area 53

5.2 Infectious Diseases 55

5.3 Oncology 56

5.4 Ophthalmology 57

5.5 Cardiovascular Disorders 58

5.6 Central Nervous System 59

5.7 Respiratory Disorders 60

5.8 Metabolic Diseases 61

5.9 Other Applications 62

6 Segmentation of Global Market by Application 63

6.1 Market Overview by Application 63

6.2 Clinical Use 65

6.3 Commercial Use 66

7 Segmentation of Global Market by Manufacturer Type 67

7.1 Market Overview by Manufacturer Type 67

7.2 Pharmaceutical Companies 69

7.3 CMOs 71

8 Segmentation of Global Market by Region 73

8.1 Geographic Market Overview 2020-2027 73

8.2 North America Market 2020-2027 by Country 77

8.2.1 Overview of North America Market 77

8.2.2 U.S. 80

8.2.3 Canada 84

8.2.4 Mexico 86

8.3 European Market 2020-2027 by Country 88

8.3.1 Overview of European Market 88

8.3.2 UK 91

8.3.3 France 93

8.3.4 Germany 95

8.3.5 Spain 97

8.3.6 Italy 99

8.3.7 Russia 101

8.3.8 Rest of European Market 103

8.4 Asia-Pacific Market 2020-2027 by Country 105

8.4.1 Overview of Asia-Pacific Market 105

8.4.2 China 108

8.4.3 Japan 110

8.4.4 India 113

8.4.5 Australia 115

8.4.6 South Korea 117

8.4.7 Rest of APAC Region 119

8.5 South America Market 2020-2027 by Country 121

8.5.1 Argentina 124

8.5.2 Brazil 126

8.5.3 Chile 128

8.5.4 Rest of South America Market 130

8.6 MEA Market 2020-2027 by Country 131

8.6.1 UAE 134

8.6.2 Saudi Arabia 136

8.6.3 South Africa 138

8.6.4 Other National Markets 140

9 Competitive Landscape 141

9.1 Overview of Key Vendors 141

9.2 New Product Launch, Partnership, Investment, and M&A 144

9.3 Company Profiles 145

Aurobindo Pharma Ltd. 145

Cambrex Corporation 147

Catalent, Inc. 148

Dr. Reddy's Laboratories Ltd. 149

GlaxoSmithKline plc 150

Lonza Group 151

Merck & Co., Inc. 152

Mylan N.V. 153

Novartis AG 154

Pfizer Inc. 155

Sun Pharmaceutical Industries Ltd. 156

Teva Pharmaceutical Industries Ltd. 157

Wuxi AppTec Co., Ltd. 158

10 Investing in Global Market: Risk Assessment and Management 159

10.1 Risk Evaluation of Global Market 159

10.2 Critical Success Factors (CSFs) 162

Related Reports and Products 165

Figure 1. Research Method Flow Chart 12
Figure 2. Breakdown of Primary Research 14
Figure 3. Bottom-up Approach and Top-down Approach for Market Estimation 16
Figure 4. Global Market Forecast in Optimistic, Conservative and Balanced Perspectives, 2020-2027 18
Figure 5. Global Small Molecule API Market, 2017-2027, $ mn 21
Figure 6. Impact of COVID-19 on Business 24
Figure 7. Primary Drivers and Impact Factors of Global Small Molecule API Market 26
Figure 8. Primary Restraints and Impact Factors of Global Small Molecule API Market 29
Figure 9. Investment Opportunity Analysis 33
Figure 10. Porter’s Fiver Forces Analysis of Global Small Molecule API Market 36
Figure 11. Breakdown of Global Small Molecule API Market by Source, 2020-2027, % of Revenue 40
Figure 12. Contribution to Global 2021-2027 Cumulative Revenue by Source, Value ($ mn) and Share (%) 41
Figure 13. Global Small Molecule API Market: Synthetic API, 2017-2027, $ mn 42
Figure 14. Global Small Molecule API Market: Branded Synthetic API, 2017-2027, $ mn 43
Figure 15. Global Small Molecule API Market: Generic Synthetic API, 2017-2027, $ mn 44
Figure 16. Global Small Molecule API Market: Semi-synthetic API, 2017-2027, $ mn 45
Figure 17. Global Small Molecule API Market: Natural Origin, 2017-2027, $ mn 46
Figure 18. Breakdown of Global Small Molecule API Market by Type, 2020-2027, % of Revenue 47
Figure 19. Contribution to Global 2021-2027 Cumulative Revenue by Type, Value ($ mn) and Share (%) 48
Figure 20. Global Small Molecule API Market: Standard API, 2017-2027, $ mn 49
Figure 21. Global Small Molecule API Market: High Potency API (HPAPI), 2017-2027, $ mn 50
Figure 22. Global Small Molecule API Market: Branded HPAPI, 2017-2027, $ mn 51
Figure 23. Global Small Molecule API Market: Generic HPAPI, 2017-2027, $ mn 52
Figure 24. Breakdown of Global Small Molecule API Market by Therapeutic Area, 2020-2027, % of Revenue 54
Figure 25. Contribution to Global 2021-2027 Cumulative Revenue by Therapeutic Area, Value ($ mn) and Share (%) 54
Figure 26. Global Small Molecule API Market: Infectious Diseases, 2017-2027, $ mn 55
Figure 27. Global Small Molecule API Market: Oncology, 2017-2027, $ mn 56
Figure 28. Global Small Molecule API Market: Ophthalmology , 2017-2027, $ mn 57
Figure 29. Global Small Molecule API Market: Cardiovascular Disorders, 2017-2027, $ mn 58
Figure 30. Global Small Molecule API Market: Central Nervous System, 2017-2027, $ mn 59
Figure 31. Global Small Molecule API Market: Respiratory Disorders, 2017-2027, $ mn 60
Figure 32. Global Small Molecule API Market: Metabolic Diseases, 2017-2027, $ mn 61
Figure 33. Global Small Molecule API Market: Other Applications, 2017-2027, $ mn 62
Figure 34. Breakdown of Global Small Molecule API Market by Application, 2020-2027, % of Revenue 63
Figure 35. Contribution to Global 2021-2027 Cumulative Revenue by Application, Value ($ mn) and Share (%) 64
Figure 36. Global Small Molecule API Market: Clinical Use, 2017-2027, $ mn 65
Figure 37. Global Small Molecule API Market: Commercial Use, 2017-2027, $ mn 66
Figure 38. Breakdown of Global Small Molecule API Market by Manufacturer Type, 2020-2027, % of Revenue 67
Figure 39. Contribution to Global 2021-2027 Cumulative Revenue by Manufacturer Type, Value ($ mn) and Share (%) 68
Figure 40. Global Small Molecule API Market: Pharmaceutical Companies, 2017-2027, $ mn 69
Figure 41. Breakdown of Global Small Molecule API In-house Synthesis Market by Region, 2020-2027, % of Revenue 70
Figure 42. Global Small Molecule API Market: CMOs, 2017-2027, $ mn 71
Figure 43. Breakdown of Global Small Molecule API Contract Synthesis Market by Region, 2020-2027, % of Revenue 72
Figure 44. Global Market Snapshot by Region 73
Figure 45. Geographic Spread of Worldwide Small Molecule API Market, 2020-2027, % of Revenue 74
Figure 46. Contribution to Global 2021-2027 Cumulative Revenue by Region, Value ($ mn) and Share (%) 75
Figure 47. North American Small Molecule API Market, 2017-2027, $ mn 78
Figure 48. Breakdown of North America Small Molecule API Market by Country, 2020 and 2027, % of Revenue 78
Figure 49. Contribution to North America 2021-2027 Cumulative Revenue by Country, Value ($ mn) and Share (%) 79
Figure 50. U.S. Small Molecule API Market, 2017-2027, $ mn 81
Figure 51. Canada Small Molecule API Market, 2017-2027, $ mn 84
Figure 52. Small Molecule API Market in Mexico, 2017-2027, $ mn 86
Figure 53. European Small Molecule API Market, 2017-2027, $ mn 89
Figure 54. Breakdown of European Small Molecule API Market by Country, 2020 and 2027, % of Revenue 89
Figure 55. Contribution to Europe 2021-2027 Cumulative Revenue by Country, Value ($ mn) and Share (%) 90
Figure 56. Small Molecule API Market in UK, 2017-2027, $ mn 91
Figure 57. Small Molecule API Market in France, 2017-2027, $ mn 93
Figure 58. Small Molecule API Market in Germany, 2017-2027, $ mn 95
Figure 59. Small Molecule API Market in Spain, 2017-2027, $ mn 97
Figure 60. Small Molecule API Market in Italy, 2017-2027, $ mn 99
Figure 61. Small Molecule API Market in Russia, 2017-2027, $ mn 101
Figure 62. Small Molecule API Market in Rest of Europe, 2017-2027, $ mn 103
Figure 63. Asia-Pacific Small Molecule API Market, 2017-2027, $ mn 106
Figure 64. Breakdown of APAC Small Molecule API Market by Country, 2020 and 2027, % of Revenue 106
Figure 65. Contribution to APAC 2021-2027 Cumulative Revenue by Country, Value ($ mn) and Share (%) 107
Figure 66. Small Molecule API Market in China, 2017-2027, $ mn 108
Figure 67. Small Molecule API Market in Japan, 2017-2027, $ mn 111
Figure 68. Small Molecule API Market in India, 2017-2027, $ mn 113
Figure 69. Small Molecule API Market in Australia, 2017-2027, $ mn 115
Figure 70. Small Molecule API Market in South Korea, 2017-2027, $ mn 117
Figure 71. Small Molecule API Market in Rest of APAC, 2017-2027, $ mn 119
Figure 72. South America Small Molecule API Market, 2017-2027, $ mn 122
Figure 73. Breakdown of South America Small Molecule API Market by Country, 2020 and 2027, % of Revenue 122
Figure 74. Contribution to South America 2021-2027 Cumulative Revenue by Country, Value ($ mn) and Share (%) 123
Figure 75. Small Molecule API Market in Argentina, 2017-2027, $ mn 124
Figure 76. Small Molecule API Market in Brazil, 2017-2027, $ mn 126
Figure 77. Small Molecule API Market in Chile, 2017-2027, $ mn 128
Figure 78. Small Molecule API Market in Rest of South America, 2017-2027, $ mn 130
Figure 79. Small Molecule API Market in Middle East and Africa (MEA), 2017-2027, $ mn 132
Figure 80. Breakdown of MEA Small Molecule API Market by Country, 2020 and 2027, % of Revenue 132
Figure 81. Contribution to MEA 2021-2027 Cumulative Revenue by Country, Value ($ mn) and Share (%) 133
Figure 82. Small Molecule API Market in UAE, 2017-2027, $ mn 134
Figure 83. Small Molecule API Market in Saudi Arabia, 2017-2027, $ mn 136
Figure 84. Small Molecule API Market in South Africa, 2017-2027, $ mn 138
Figure 85. Growth Stage of Global Small Molecule API Industry over the Forecast Period 141

Table 1. Snapshot of Global Small Molecule API Market in Balanced Perspective, 2020-2027 19
Table 2. Growth Rate of World GDP, 2020-2022 23
Table 3. Main Product Trends and Market Opportunities in Global Small Molecule API Market 32
Table 4. Global Small Molecule API Market by Source, 2017-2027, $ mn 40
Table 5. Global Small Molecule API Market: Synthetic API by Drug Type, 2017-2027, $ mn 42
Table 6. Global Small Molecule API Market by Type, 2017-2027, $ mn 47
Table 7. Global Small Molecule API Market: HPAPI by Drug Type, 2017-2027, $ mn 50
Table 8. Global Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 53
Table 9. Global Small Molecule API Market by Application, 2017-2027, $ mn 63
Table 10. Global Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 67
Table 11. Global Small Molecule API Market by Region, 2017-2027, $ mn 74
Table 12. Leading National Small Molecule API Market, 2020 and 2027, $ mn 76
Table 13. North America Small Molecule API Market by Country, 2017-2027, $ mn 79
Table 14. U.S. Small Molecule API Market by Type, 2017-2027, $ mn 82
Table 15. U.S. Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 82
Table 16. U.S. Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 82
Table 17. Canada Small Molecule API Market by Type, 2017-2027, $ mn 85
Table 18. Canada Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 85
Table 19. Canada Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 85
Table 20. Mexico Small Molecule API Market by Type, 2017-2027, $ mn 87
Table 21. Mexico Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 87
Table 22. Mexico Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 87
Table 23. Europe Small Molecule API Market by Country, 2017-2027, $ mn 90
Table 24. UK Small Molecule API Market by Type, 2017-2027, $ mn 92
Table 25. UK Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 92
Table 26. UK Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 92
Table 27. France Small Molecule API Market by Type, 2017-2027, $ mn 94
Table 28. France Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 94
Table 29. France Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 94
Table 30. Germany Small Molecule API Market by Type, 2017-2027, $ mn 96
Table 31. Germany Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 96
Table 32. Germany Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 96
Table 33. Spain Small Molecule API Market by Type, 2017-2027, $ mn 98
Table 34. Spain Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 98
Table 35. Spain Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 98
Table 36. Italy Small Molecule API Market by Type, 2017-2027, $ mn 100
Table 37. Italy Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 100
Table 38. Italy Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 100
Table 39. Russia Small Molecule API Market by Type, 2017-2027, $ mn 102
Table 40. Russia Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 102
Table 41. Russia Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 102
Table 42. Small Molecule API Market in Rest of Europe by Country, 2017-2027, $ mn 104
Table 43. APAC Small Molecule API Market by Country, 2017-2027, $ mn 107
Table 44. China Small Molecule API Market by Type, 2017-2027, $ mn 109
Table 45. China Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 109
Table 46. China Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 109
Table 47. Japan Small Molecule API Market by Type, 2017-2027, $ mn 112
Table 48. Japan Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 112
Table 49. Japan Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 112
Table 50. India Small Molecule API Market by Type, 2017-2027, $ mn 114
Table 51. India Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 114
Table 52. India Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 114
Table 53. Australia Small Molecule API Market by Type, 2017-2027, $ mn 116
Table 54. Australia Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 116
Table 55. Australia Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 116
Table 56. South Korea Small Molecule API Market by Type, 2017-2027, $ mn 118
Table 57. South Korea Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 118
Table 58. South Korea Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 118
Table 59. Small Molecule API Market in Rest of APAC by Country/Region, 2017-2027, $ mn 120
Table 60. South America Small Molecule API Market by Country, 2017-2027, $ mn 123
Table 61. Argentina Small Molecule API Market by Type, 2017-2027, $ mn 125
Table 62. Argentina Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 125
Table 63. Argentina Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 125
Table 64. Brazil Small Molecule API Market by Type, 2017-2027, $ mn 127
Table 65. Brazil Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 127
Table 66. Brazil Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 127
Table 67. Chile Small Molecule API Market by Type, 2017-2027, $ mn 129
Table 68. Chile Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 129
Table 69. Chile Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 129
Table 70. MEA Small Molecule API Market by Country, 2017-2027, $ mn 133
Table 71. UAE Small Molecule API Market by Type, 2017-2027, $ mn 135
Table 72. UAE Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 135
Table 73. UAE Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 135
Table 74. Saudi Arabia Small Molecule API Market by Type, 2017-2027, $ mn 137
Table 75. Saudi Arabia Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 137
Table 76. Saudi Arabia Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 137
Table 77. South Africa Small Molecule API Market by Type, 2017-2027, $ mn 139
Table 78. South Africa Small Molecule API Market by Therapeutic Area, 2017-2027, $ mn 139
Table 79. South Africa Small Molecule API Market by Manufacturer Type, 2017-2027, $ mn 139
Table 80. Aurobindo Pharma Ltd.: Company Snapshot 145
Table 81. Aurobindo Pharma Ltd.: Business Segmentation 145
Table 82. Aurobindo Pharma Ltd.: Product Portfolio 146
Table 83. Aurobindo Pharma Ltd.: Revenue, 2017-2019, $ mn 146
Table 84. Risk Evaluation for Investing in Global Market, 2020-2027 160
Table 85. Critical Success Factors and Key Takeaways 163

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Global Small Molecule API Market 2020-2027

Global Small Molecule API Market 2020-2027